This Formula Is Based on the Latest Anti-Aging Research
Every single active ingredient contained in this formula is backed by multiple clinical research studies. We have done our homework, and we are proud to detail below the clinical research data that supports the inclusion of every active ingredient in this formula.
Soy Lecithin
Lecithin is a naturally-occurring group of phospholipids that's found in nearly every living cell. Though the word lecithin is derived from the Greek "lekithos", which means "yolk of an egg," the primary commercial source of lecithin as a food ingredient comes from the soybean. Lecithin is particularly rich in choline, a compound known to have a number of functions within the body.
In 1996, a French research group demonstrated that lecithin in the diet could lower the total and HDL-cholesterol level. They believed that the cholesterol-lowering effect of lecithin was related to hepatic microsomal pools of phosphatidylcholine and cholesterol. (Polichetti E. et al, Cholesterol-lowering effect of soyabean lecithin in normolipidaemic rats by stimulation of biliary lipid secretion. Br J Nutr. 1996 Mar;75(3):471-8.)
Can lecithin help you stop losing your car keys? Scientific research has found that lecithin and in particular, the choline it contains, may improve your memory, especially mild memory loss associated with getting older. Lecithin and other choline-containing compounds enhance memory in normal adults, particularly in those individuals having relatively poor memory function to start with.
Scientists have known for some time that choline is essential to liver function and health. Even a few weeks on a choline-deficient diet can result in a fatty liver, which can lead to cirrhosis or to cancer of the liver. Besides contributing choline, lecithin also appears to directly protect the liver from cirrhosis associated with excessive alcohol consumption.
Spirulina
Spirulina is a tiny aquatic plant that is 60% highly bioavailable protein, essential vitamins and phytonutrients such as beta-carotene, the rare essential fatty acid GLA (gamma-linolenic acid), sulfolipids, glycolipids and polysaccharides. Its deep blue-green color comes from its rainbow of natural pigments — chlorophyll (green), phycocyanin (blue) and carotenoids (orange) — that harvest the sun's energy. It is also easy to digest, so the nutrients it contains can be readily absorbed.
Spirulina is known as a “superfood.” It is considered to be one of the most nutritious, concentrated whole foods known to humankind. This green food is a good plant source of protein, carotenoids, and many essential vitamins and minerals, including vitamin B12.
While spirulina research conducted over the years has clearly shown its multi-faceted health promoting effects, one recent study in the areas of immunomodulation is big news!
The study demonstrated that spirulina was able to raise the levels of three cytokines (specialized proteins produced by immune system lymphocytes) particularly one form of interferon (IFN)-y, to 13.6 times basal levels, and two forms of interleukins, (IL)-1 beta to 3.3 times basal levels, and IL-4, to two times basal levels.
Earlier, the results of the Baojiang study, given at the Second Asia-Pacific Conference on Algal Biotechnology in 1994, concluded that polysaccharides of spirulina platensis, at the dosage of 150-300 mg/kg by injection or taken orally, can increase the percentage of T-lymphocyte in the blood. The results demonstrate that spirulina polysaccharides can improve cellular and humoral immunity.
Spirulina has also been shown to bind to reactive oxygen species (ROS), such as hydroxyl free radicals, which may result in antioxidant effects.
Alfalfa
Alfalfa is a member of the legume group. Alfalfa, also known as Medicago sativa, is a green grass full of fiber and trace minerals. It's most commonly used to support good digestion and elimination. The juice is rich in minerals and chlorophyll and its trace minerals may be key factors in rebuilding and repairing joint tissue.
Research has shown that alfalfa may be able to lower total cholesterol and low-density lipoprotein (LDL) in patients with high cholesterol levels (Mölgaard, von Schenck, et al. Atherosclerosis. 1987 May;65(1-2):173-9.) According to another study, alfalfa seems to be able to lower basal glucose levels and initially decrease insulin deficiency in subjects with diabetes. (Swanston-Flatt, Day, et al. Diabetologia. 1990 Aug;33(8):462-4.)
Wheat Grass
Wheat grass is a nutrient-dense green food that is highly valued by health-conscious individuals as a great natural source of nutrients. Wheat grass is high in chlorophyll, calcium, magnesium and potassium.
Wheat grass is grown from wheat berries and is harvested after just seven days of growth. Due to its fibrous nature, which is indigestible by humans, wheat grass must be liquefied through the use of a juicer before it can be consumed.
It is the chlorophyll in wheat grass that is perhaps its most valuable asset. Chlorophyll, the green pigment that is often referred to as the “blood of plants,” has been shown in studies to have a cleansing, detoxifying and healing effect on the body. Research in Japan has shown that chlorophyll provides some protection from carcinogens. This protection is said to come from its ability to strengthen cells, detoxify the liver and bloodstream, and chemically neutralize pollutants. High-chlorophyll beverages are often included in diets purported to treat ailments such as rheumatoid arthritis. (Rauma, Nenonen, Eur J Clin Nutr. 1993 Oct;47(10):747-9.)
Wheat grass has also been shown to have anti-inflammatory activity, which may be the reason for its use for treatment of various gastrointestinal, arthritic and other conditions (Ben-Arye, Goldin et al. Scand J Gastroenterol. 2002 Apr;37(4):444-9.)
Barely Grass
Barley grass is the leaf portion of the barley plant that remains after the seeds have been removed. It is rich in chlorophyll and high in antioxidant activity. It contains many nutrients that strengthen and maintain the immune system, has a cleansing effect on cells and may neutralize heavy metals like mercury.
Carrot
The carrot is among the best dietary sources of beta-carotene. Beta-carotene is a member of the carotenoid family, which also includes lutein, lycopene and zeaxanthin. Carotenoids are a class of highly pigmented fat-soluble antioxidants found in plants. While all have antioxidant power, beta-carotene is a precursor to vitamin A. Beta-carotene is converted to vitamin A in the liver. The conversion of beta-carotene to vitamin A is dependent on several biological factors, so each individual will have varying rates. According to Betty Burri, a biochemist of the USDA and the University of California at Davis, people convert from 0% to at best 11% of beta-carotene into vitamin A. (Am J Clin Nutr. 2002 May;75(5):900-7.)
Since not everyone converts sufficient amounts of beta-carotene into vitamin A, why should we take it in a multi-vitamin formula? Beta-carotene has a number of immune-enhancing properties. Originally, it was thought that these effects were due to beta-carotene being converted into vitamin A in the body. The benefits of taking beta-carotene far outreach just its conversion to vitamin A. (Am J Clin Nutr. 1994 Dec;60(6):969-72. Am J Clin Nutr. 1997 Mar;65(3):871-5.)
Population-based studies have clearly demonstrated the effectiveness of a diet high in beta-carotene in protecting against a variety of cancers. Research has indicated that in order for beta-carotene to be effective against cancer, it must be taken with other antioxidant nutrients such as vitamins E and C and selenium. It is thought that beta-carotene is more effective against cancer than vitamin A, due to its antioxidant and immune-stimulating properties. (Ann Intern Med. 2006 Sep 5;145(5):372-85. Epub 2006 Jul 31. Cochrane Database Syst Rev. 2004 Oct 18;(4):CD004183.)
Barley Malt
Barley malt is a natural sweetener derived from an extract of sprouted barley. As a sugar substitute, barley malt is a natural whole food.
Broccoli
Broccoli is a member of the cabbage family, and is closely related to cauliflower. Like other cruciferous vegetables, broccoli contains sulforaphane and indoles, which have significant anti-cancer effects. Research on indole-3-carbinol shows this compound helps deactivate a potent estrogen metabolite (4-hydroxyestrone) that promotes tumor growth, especially in estrogen-sensitive breast cells, while at the same time increasing the level of 2-hydroxyestrone, a form of estrogen that can be cancer-protective. Indole-3-carbinol has been shown to suppress not only breast tumor cell growth, but also cancer cell metastasis.
Brown Rice Bran
Brown rice bran is being hailed as a new superfood. Rice bran contains quite an amazing number of nutrients. Some researchers claim that brown rice bran may contain over 120 antioxidants. It also contains an astounding quantity of other health-giving nutrients. Rice bran contains phytosterols, polysaccharides, beta-sitosterol, fiber, vitamin E and B vitamins. These include the rare B15, a vital antioxidant.
Apple Fiber and Apple Pectin
By improving digestive regularity, apple fiber (insoluble) and apple pectin (a form of soluble fiber) may provide health benefits ranging from lowering cholesterol and improving heart health to bolstering immunity.
Apples act as antioxidants against the damaging portion of cholesterol in your blood stream. They work in any form (from raw to juice) to maintain good cardiovascular health. Apple pectin is especially effective in lowering cholesterol levels.
Oat Bran
Oat bran is the edible, outermost layer of the oat kernel. Oats have been recognized as both a food and a medicinal herb. Like oatmeal, oat bran contains B-complex vitamins, proteins, fats, minerals, and heart-healthy soluble fiber. When eaten regularly, oatmeal and oat bran may help to lower total cholesterol levels by 25 points or more within a very short time period (one to three months). In addition, oat bran can help to reduce the bad LDL and raise levels of good HDL cholesterol.
Oat bran is rich in a soluble fiber called beta glucan. In 1997, the U.S. Food and Drug Administration passed a unique ruling that allowed oat bran to be registered as the first cholesterol-reducing food at an amount providing 3 grams of beta glucan per day, although some evidence suggests this level may not be high enough to make a significant difference. Several trials have shown that oat bran supplementation can significantly lower cholesterol levels in people with elevated cholesterol, but only slightly in people with healthy cholesterol levels.
Chlorella
Chlorella can be considered a true superfood. It is a special algae called Pyrenoidosa that grows in fresh water and has the highest content of chlorophyll (28.9g/kg) of any known plant on earth. It is extremely high in enzymes, vitamins and minerals. It has been shown to activate macrophages that scavenge and digest cancer cells, foreign proteins and chemicals.
Among its antioxidant properties, chlorella has been shown to remove heavy metals and other synthetics from the body by actually binding with them so they may be pulled from the bloodstream and safely excreted out of the body.
Chlorella may offer relief to people suffering from fibromyalgia. Preliminary clinical research shows subjective improvements in general symptom and pain scores in people with fibromyalgia taking chlorella tablets plus a liquid extract containing malic acid daily for two months. (Merchant, RE, Phytother Res. 2000 May;14(3):167-73.)
Red Beet
Red beets are loaded with antioxidants. Betacyanin is the pigment that gives beets their red color, this pigment is also a powerful cancer fighting agent.
In stomach cancer patients, when scientists compared the effects of fruit and vegetable juices on the formation of nitrosamines, cancer-causing compounds produced in the stomach from chemicals called nitrates, beet juice was found to be a potent inhibitor of the cell mutations caused by these compounds. Nitrates are commonly used as a chemical preservative in processed meats.
Red beets can also lower your blood pressure. A new study foun red beets help lower blood pressure the same way nitroglycerin does—by relaxing blood vessels. People who drank two cups of red beet juice had a drop in blood pressure that averaged 10.4 points at its peak. And 24 hours later blood pressure was still six points lower. Beets contain nitrates, which convert to nitric oxide, a substance that dilates blood vessels. (Webb, AJ et al. Hypertension. published online Feb 4, 2008; DOI: 10.1161/HYPERTENSIONAHA.107.103523.)
Panax Ginseng
Ginseng is best known as an "adaptogen", which is a substance that may help individuals cope with physical and emotional stress. A part of traditional Chinese medicine for thousands of years, panax ginseng has been used to treat almost every possible ailment. Currently, it is used extensively in many Asian countries as an everyday tonic to maintain overall health as well as to treat illnesses, including heart conditions.
The main active components of panax ginseng are ginsenosides, which have been shown to have a variety of beneficial effects, including anti-inflammatory, antioxidant and anticancer effects. Results of clinical research studies demonstrate that panax ginseng may improve psychological function, immune function and conditions associated with diabetes.
A study of 227 healthy volunteers demonstrated that daily administration of 100 mg of G115 for 12 weeks enhanced the efficacy of polyvalent influenza vaccine. The patients who received ginseng had a lower incidence of influenza and colds, higher antibody titers and higher natural killer cell activity levels. (Scaglione F, Cattaneo G, Alessandria M, Cogo R. Efficacy and safety of the standardized Ginseng extract G115 for potentiating vaccination against the influenza syndrome and protection against the common cold [corrected]. Drugs Exp Clin Res. 1996;22:65-72.)
Eleuthero
Eleuthero is a distant relative of panax ginseng. Also known commonly as touch-me-not and devil’s shrub, eleuthero has been most frequently nicknamed Siberian ginseng in this country. The root and the rhizomes (underground stem) are used medicinally. Eleuthero’s benefits are similar to panax ginseng, as it has been shown to increase endurance and fortify the immune system.
Peppermint
Peppermint and peppermint oil have been used historically for numerous health conditions, including common cold symptoms, cramps, headache, indigestion, joint pain and nausea.
Research now supports the use of peppermint oil as safe and effective. According to the reports, peppermint oil is shown to relax the smooth muscles in the gastrointestinal tract, providing relief of bloating, flatulence (gas) and abdominal pain.
Green Tea
Green tea is produced from the Camellia sinensis plant, from which black tea is also produced. The difference between green and black tea is that with green tea, the leaves are steamed when fresh, which does not allow for the oxidation which occurs with black tea. Because oxidation does not take place, the green tea leaves are higher in polyphenols with potent antioxidant and anticancer properties.
Is there anything green tea can't do? A flurry of new studies suggests that green tea has wide-spectrum activity against heart disease, infections, diabetes, high blood pressure, age-related cognitive decline, Alzheimer's disease, osteoporosis, arthritis, gum disease, weight gain and more.
Green tea possesses unique antioxidants (mainly EGCG or epigallocatechin gallate and catechins) that act as highly potent antioxidant agents, artery and heart protectors, blood-sugar regulators, cholesterol and blood pressure reducers, antiviral and antibacterial agents, immune boosters, anti-inflammatories, calorie and fat burners, brain cell guardians and overall inhibitors of the aging process.
Royal Jelly
Royal Jelly is a substance of complex chemical structure produced by the young nurse bees as larva food.
This rich concentrated food is not just useful for the bees. It contains remarkable amounts of proteins, lipids, glucides, vitamins, hormones, enzymes, mineral substances and specific vital factors that act as biocatalysts in cell regeneration processes within the human body.
Although some of the elements found in royal jelly are in microgram quantities, they still can act supremely with coenzymes as catalysts or can act synergistically. Royal jelly is rich in protein, vitamins and minerals. There is very little clinical data available for royal jelly at this time. It is primarily used for the high amount of nutrients that it contains.
Fructooligosaccharides
Fructooligosaccharides (FOS) refer to a class of non-digestible carbohydrates or sugars that occur naturally in a wide variety of foods throughout the plant kingdom. Since they are non-digestible, they pass through the human digestive virtually unchanged. When the fructooligosaccharides reach the colon, they are used by the good or beneficial bacteria found there (known as bifidobacteria or bifidus) for growth and multiplication. A healthy population of these beneficial bacteria in the digestive tract enhances the digestion and absorption of nutrients, detoxification and elimination processes and helps boost the immune system. (J Nutr. 2007 Dec;137(12):2763-8.)
Fructooligosaccharides can also help maintain a healthy balance of the "good" bacteria with the "bad" bacteria in the digestive tract. When the "bad" bacteria dominates, a condition known as "dysbiosis" can occur. Dysbiosis can then lead to other problems throughout the body. Fructooligosaccharides may also be of benefit in helping to relieve constipation and other gastrointestinal disorders, including problems related to irritable bowel syndrome, inflammatory bowel disease and lactose intolerance.
Trace Minerals
There are two kinds of minerals: macrominerals and trace minerals. Macro means "large" in Greek (and your body needs larger amounts of macrominerals than trace minerals). The macromineral group is made up of calcium, phosphorus, magnesium, sodium, potassium, chloride and sulfur.
Even though your body needs trace minerals, it needs just a tiny bit of each one. Scientists aren't even sure how much of these minerals you need each day. Trace minerals include iron, manganese, copper, iodine, zinc, cobalt, fluoride and selenium.
Trace minerals have numerous roles. Oftentimes, because these minerals are found in such small quantities in the body, scientists and physicians have paid little attention to their importance in health and disease prevention. However, with the advent of improved science and the recognition of the efficacy of natural medicine, we are beginning to understand how vital these elements are to our health. Trace minerals are important in the proper functioning of enzyme systems, nerve conduction and muscle function, assisting with transfer of nourishment into cells, providing the framework for tissues, and regulation of organ functions. These functions are not possible without a constant, adequate supply of these vital minerals.
Milk Thistle
Milk thistle has been used since Greco-Roman times as an herbal remedy for a variety of ailments, particularly liver problems. In the late 19th and early 20th centuries, physicians in the U.S. used milk thistle seeds to relieve congestion of the liver, spleen and kidneys. Today, several scientific studies suggest that active substances in milk thistle (particularly silymarin) protect the liver from damage caused by viruses, toxins, alcohol and certain drugs, such as acetaminophen.
Many professional herbalists recommend milk thistle extract for the prevention and/or treatment of various liver disorders including viral hepatitis, fatty liver associated with long term alcohol use, and liver damage from drugs and industrial toxins such as carbon tetrachloride.
Many of the studies on milk thistle have been small and poorly coordinated. There are currently larger and better controlled studies being conducted at NIH and other institutions. Smaller studies have shown milk thistle extracts to be effective as an anti-inflammatory and to possess anti-carcinogenic activity. (Barve A. Ann Hepatol. 2008 Jan-Mar;7(1):5-15. Review.)
Kelp
Kelp are large seaweeds that are most known for their high iodine content. They are also good sources of vitamins and minerals. Kelp is used to treat a number of different health concerns. It is used to treat iodine deficiency, thyroid disorders, obesity, arthritis, digestive disorders, along with other health issues.
Preliminary research indicates that kelp may have antimicrobial and antioxidant activity (Criado, Ferreirós, Rev Esp Fisiol. 1984 Jun;40(2):227-30) (Rupérez, Ahrazem et al, J Agric Food Chem. 2002 Feb 13;50(4):840-5).
Ginkgo Biloba
Ginkgo biloba is a powerful antioxidant herb best known for its brain-boosting properties. It has been used medicinally for thousands of years and is one of the best selling herbs today in the U.S. One of its main functions is its ability to enhance circulation. It has the ability to increase oxygen supply to the brain, heart and all other body parts. (Heiss WD. Bull Schweiz. Akad Med Wiss. 1980 Apr;36(1-3):183-207. Wu Y et al. Planta Med. 2007 Jun;73(7):624-8.)
Ginkgo is also known to have anti-aging properties. (Chan PC et al. J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2007 Jul-Sep;25(3):211-44.) It also may lower blood pressure (Jezova D et al. J Physiol Pharmacol. 2002 Sep;53(3):337-48.) and inhibit blood clotting. (Please note: One should consult a doctor before using ginkgo biloba in combination with blood-thinning medications.)
There have been several studies that indicate the positive effects of using ginkgo for dementia. Overall, the scientific literature suggests that ginkgo may be beneficial to people with the early stages of Alzheimer’s disease and dementia. (Ahlemeyer B, Krieglstein J. Cell Mol Life Sci. 2003 Sep;60(9):1779-92. McKenna DJ, Jones K, Hughes K. Altern Ther Health Med. 2001 Sep-Oct;7(5):70-86, 88-90.)
Research has suggested that ginkgo may improve eye blood flow, and possibly help glaucoma and macular degeneration. (Wimpissinger B et al. Acta Ophthalmol Scand. 2007 Jun;85(4):445-9.)
Grape Seed Extract
Extracts from the skin surrounding the seeds of red grapes contain proanthocyanidins, one of the most beneficial groups of plant flavonoids. These powerful antioxidants have been shown to have up to 50 times the free radical fighting activity of vitamins C and E. Proanthocyanidins are particularly effective at fighting against free radicals because their chemical structure allows them to be incorporated into cell membranes in the body and to protect the cell from damage by both fat- and water-soluble free radicals. These antioxidants are thought to offer protection against heart disease, cancer, accelerated aging and other diseases linked to oxidative damage. Several studies have indicated that heart disease is less frequent in people who consume higher levels of dietary flavonoids. (Mutat Res. 2003 Feb-Mar;523-524:87-97. Ann N Y Acad Sci. 2002 May;957:260-70. Ann N Y Acad Sci. 2002 May;957:250-9.)
CoQ10
CoQ10 is a powerful, fat-soluble, vitamin-like substance synthesized in the membranes of cells. It is found mostly in mitochondria, the cell’s “power plant.” It is an essential part of the energy-producing process known as the electron transport chain. It acts as kind of a spark plug, assisting in the generation of adenosine triphosphate (ATP), the body’s basic energy currency. Without adequate CoQ10, cells cannot make the energy they need to sustain life. Eventually, your whole body suffers the malaise of low energy production. (Mitochondrion. 2007 Jun;7 Suppl:S51-61. Epub 2007 Mar 30.)
It is a potent antioxidant and energy booster, first identified in 1957 and widely used in Japan for the treatment of cardiovascular disease. Since it is in every cell, supplemental CoQ10 has a wide potential of uses–from helping a failing heart work better to slowing the decline of Parkinson’s disease. (Nutr Rev. 2007 Jun;65(6 Pt 1):286-93. Mitochondrion. 2007 Jun;7 Suppl:S146-53. Epub 2007 Mar 27.) Research indicates it can reduce the severity of migraine headaches, improve blood sugar control in diabetics, and even help stop the spread of cancer and improve immune function in AIDS. (Vitam Horm. 2004;69:297-312. Eur J Clin Nutr. 2002 Nov;56(11):1137-42. Biofactors. 1999;9(2-4):365-70.)
After the age of 30, natural levels of CoQ10 begin to diminish. By the age of 80, your CoQ10 levels may be lower than they were at birth. Further loss may come from stress, illness and some medications such as cholesterol-lowering statin drugs, oral hypoglycemic drugs such as glyburide, phenformin and tolazamide and beta-blockers. (Mitochondrion. 2007 Jun;7 Suppl:S168-74. Epub 2007 Mar 27. J Hum Hypertens. 1999 Mar;13(3):203-8. Heart Lung Circ. 2007;16 Suppl 3:S56-64. Epub 2007 Jul 6.)
Alpha Lipoic Acid
Alpha lipoic acid is exceptionally potent, ranking above even vitamins E and C in antioxidant activity. (Gen Pharmacol. 1997 Sep;29(3):315-31.) It has unique abilities to enter the brain, and help rev up mental and physical energy. It shows promise in helping prevent and repair degeneration of brain cells and to slow progression of neurodegenerative diseases, such as Alzheimer's. (Pharmacol Ther. 2007 Jan;113(1):154-64. Epub 2006 Sep 20. Ann Clin Psychiatry. 2005 Oct-Dec;17(4):269-86. Front Biosci. 2004 Sep 1;9:3447-52.)
Dr. Lester Packer, University of Southern California, calls alpha lipoic acid a "universal" antioxidant that offers protection against an aging brain, declining memory, strokes, heart disease, cancer and cataracts. In high doses (200-600 mg daily), alpha lipoic acid is used to prevent and lessen the symptoms of diabetic neuropathy. (Free Radic Biol Med. 1997;22(1-2):359-78. Nutrition. 2001 Oct;17(10):888-95.)
Alpha lipoic acid works best as an anti-aging agent as part of a network of other antioxidants, such as vitamin E and C and CoQ10.
Note: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
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