Acetyl-L-Carnitine Capsules - 500 MG

Product Highlights

• Made with 100% Carnipure™, one of the highest quality, most researched and purest forms

• Provides a clinical dose of 500 mg of pure acetyl-L-carnitine. We also offer a 1,000 mg dosage formula.

• Clinically proven to boost overall energy levels by helping to restore normal cellular energy production

• Plays an important role in revitalizing the aging brain and slowing cognitive decline

• A potent antioxidant that is especially effective at preventing damage to brain cell mitochondria

• Made in the USA in an FDA inspected facility to meet the stringent standards of US Pharmacopeia (USP) for quality, purity, potency and disintegration

Product Overview

Research shows that blood levels of acetyl-L-carnitine steadily decline after age 40 in humans. Lacking acetyl-L-carnitine, the cellular mitochondria don't burn as brightly or as robustly, triggering a kind of massive but gradual brown out that hits billions of cells simultaneously. Understandably, this prompts a slowdown in the body's mental and physical activity, which is a hallmark of aging. We highly recommend our Acetyl-L-Carnitine formula for anyone who feels as if they have lost mental and physical energy, especially since side effects are virtually non-existent.

Acetyl-L-carnitine (ALC) is an amino acid that provides fuel for cellular energy production. It helps control enzymes that keep the cells' energy centers, called mitochondria, stocked with fuel. Research has shown that acetyl-L-carnitine, a cousin of L-carnitine, which is commonly sold as a body-building supplement, is far more biochemically powerful in controlling damage to and revitalizing mitochondria.

Recent research has catapulted acetyl-L-carnitine into the scientific spotlight as a potential enhancer of mental and physical energy, both alone and especially with alpha lipoic acid (which is found in all of our Multi Nutrient Formulas as well as our Brain Energizer Formula). Studies have shown that free radical damage to mitochondria may be substantially curbed by taking a combination of acetyl-L-carnitine and alpha lipoic acid.

Acetyl-L-carnitine energizes and rejuvenates the brain. It has long been used as a mental stimulant in Europe, and research has shown that acetyl-L-carnitine may help to prevent age-related deterioration of brain cells. As well, there has been new research showing that acetyl-L-carnitine may delay the progression of age-related cognitive decline. Studies have shown that older people taking acetyl-L-carnitine experience a reduction of mental and physical fatigue, as well as improvement in their cognitive and physical functioning.

What Makes Stop Aging Now's Acetyl-L-Carnitine Superior?

• Our premium grade Acetyl-L-Carnitine is made with 100% Carnipure™, one of the highest quality, most researched and purest forms.

• Carnipure is the only form of acetyl-L-carnitine produced using a unique fermentation-based process which mimics the way acetyl-L-carnitine is produced in nature.

• Provides a clinical dose of 500 mg per daily dose. (We also offer a 1,000 mg dosage formula).

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The Supplements That Science Created

Since our founding in 1995, our philosophy has been centered around a "show us the proof" approach. Every single active ingredient contained in our formulas is backed by strong clinical evidence supporting its anti-aging properties and total body wellness attributes. More importantly, we use the exact doses and exact brands used in the research studies. Read about the research behind the formula to see exactly why we have carefully selected each ingredient. At Stop Aging Now, our research team reviews over 2,000 clinical studies per year, and our writers report on over 500 of them. These reports can be found in our News & Research section. No other company stays on top of the latest science as thoroughly as we do. You are guaranteed a clinically proven and truly effective dietary supplement. We also believe food plays a key role in longevity, which is why we create delicious Anti-Aging Recipes for our customers, to complement our superior supplements.

Quality You Can Trust

Equally important to potency and effectiveness, you get the reassuring comfort of Stop Aging Now's legendary quality. All of our premium products are made in the USA in a state-of-the art FDA inspected facility to meet the stringent standards of US Pharmacopeia (USP) for quality, purity, potency and disintegration. Most supplements are made to far lower standards. Additionally, and unfortunately, many companies keep their costs down by outsourcing production to third world countries where quality controls and regulations are virtually non-existent. Whether you take our premium products or those from another company, we strongly encourage to you to be sure to know where they are manufactured. If the bottle label doesn't say "Made in the USA", they are most likely not. Our manufacturing facilities are located in California, Illinois and Florida. We invite you to take a virtual tour of one of our facilities.

Our Customer's Success Stories Say It All!

Join the Stop Aging Now family! With over 1 million bottles sold, our success and growth is mostly due to word-of-mouth recommendations from our loyal customers. We highly recommend you read some of the hundreds of Testimonials we receive every year. By offering superior products, excellent customer service, free access to Certified Nutrition Experts and a 180-day "any reason" return policy, we keep our customers happy, order after order.

Note: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

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Supplement Facts:

Serving size: 2
Servings per bottle: 30 (1 month supply)
Each bottle contains: 60 veggie capsules

Directions: 2 capsules daily as a dietary supplement, preferably soon before or after eating food for maximum absorption.

Helpful Tip: Hover over any of the ingredients and a box will pop up giving you more detailed information.

Each serving contains:	Amount	% Daily Value
Acetyl-L-Carnitine (from Carnipure™)	500 mg	*

 *Daily Value not established

Other ingredients: Vegetable cellulose, silicon dioxide, vegetable magnesium stearate.

Other information: Free of corn, milk, yeast, wheat, sugar, artificial colors, preservatives and animal products. Kosher.

Quality Pledge: Made in the USA in an FDA inspected facility to meet the stringent standards of US Pharmacopeia (USP) for quality, purity, potency and disintegration.

Warnings: For adults only. If you are on medications, pregnant or nursing a baby, consult a health care physician prior to taking any supplement.

This Formula Is Based on the Latest Anti-Aging Research
Every single active ingredient contained in this formula is backed by multiple clinical research studies. We have done our homework, and we are proud to detail below the clinical research data that supports the inclusion of every active ingredient in this formula.

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Acetyl-L-Carnitine

Acetyl-L-carnitine is an amino acid that is "high octane cellular fuel." It has long been used as a mental stimulant in Europe. Studies have indicated that acetyl-L-carnitine (ALC) may help to prevent age-related deterioration of brain cell energy factories called mitochondria. (Ann N Y Acad Sci. 2004 Nov;1033:108-16.) Studies have also found that ALC has been beneficial in those with mild cognitive impairment, early Alzheimer's disease, geriatric mild depression, diabetic neuropathy, attention-deficit hyperactivity disorder, chronic fatigue syndrome and fatigue associated with multiple sclerosis. (Altern Med Rev. 1999 Dec;4(6):438-41. Altern Med Rev. 2005 Dec;10(4):268-93.) One of the most impressive pieces of research found that older people taking acetyl-l-carnitine experienced a reduction of mental and physical fatigue, as well as improvement in their cognitive and physical functioning. (Arch Gerontol Geriatr. 2008 Mar-Apr;46(2):181-90.)

Why is acetyl-L-carnitine better than L-carnitine?

ALC, a cousin of L-carnitine, is unique and far more biochemically powerful than L-carnitine in controlling damage to and revitalizing the mitochondria. (Pharmacol Res. 1996 Nov-Dec;34(5-6):219-24. J Nutr Biochem. 2006 Feb;17(2):73-88.) Specifically, ALC is able to enter nerve cells far better than L-carnitine can, explaining ALC's profound benefits in the brain because it-not L-carnitine— combines chemically with choline to produce acetylcholine, a neurotransmitter critical to memory and other mental functioning. (Altern Med Rev. 1999 Dec;4(6):438-41.)

The research on acetyl-L-carnitine has been exciting. A major review of the evidence (a meta-analysis) by a group at the Imperial College University in London, found that ALC significantly slowed the progression of cognitive impairment associated with aging. The improvements were clear in both psychometric testing and daily activities. Increased benefits of ALC showed up in three months and increased over time. (Montgomery SA, Int Clin Psychopharmacol 2003 Mar; 18(2): 61-71.)

Leading researcher Dr. Bruce Ames, University of California at Berkeley, is a proponent of ALC. He says there is evidence that acetyl-L-carnitine may help energize and rejuvenate the brain. He advises taking acetyl-L-carnitine along with alpha lipoic acid. The reason: According to studies conducted by Dr. Ames in collaboration with Tory Hagen at the Linus Pauling Institute at Oregon State University, the combination of acetyl-L-carnitine and alpha lipoic acid show that they may produce greater revivals of mental and physical activity than either supplement alone. (Proc Natl Acad Sci USA. 2002 Feb 19;99(4):1870-5. Proc Natl Acad Sci USA. 2002 Feb 19;99(4):2356-61.)

Maximize the potential of ALC!

Be sure to maximize the potential of acetyl-L-carnitine by adding alpha lipoic acid. The potency of acetyl-L-carnitine is enhanced when taken along with alpha lipoic acid (Redox Rep. 2008;13(1):2-10. FASEB J. 2007 Nov;21(13):3756-62.) which is found in potent doses in all of our Multi Nutrient Formulas and our Brain Energizer Formula.

How does acetyl-L-carnitine work?

ALC helps control enzymes that keep the cells' mitochondrial furnaces stocked with fuel. As bodies age, their carnitine levels plunge. "Carnitine is badly depleted during aging," says Dr. Hagen. Research shows blood levels of ALC steadily decline after age 40 in humans. Lacking carnitine, the cellular factories don't burn as brightly or as robustly, triggering a kind of massive but gradual brown out that hits billions and billions of cells simultaneously. Understandably, this prompts a slowdown in the body's mental and physical activity, which is a hallmark of aging. (Proc Natl Acad Sci USA. 2002 Feb 19;99(4):1870-5. Proc Natl Acad Sci USA. 2002 Feb 19;99(4):2356-61. FASEB J. 2007 Nov;21(13):3756-62.)

Dr. Ames became fascinated by acetyl-L-carnitine, which he noted in the mid-1990's was being sold in Rome as a "pick-me-up" supplement. It makes sense, Ames says, because ALC fires up cellular furnaces by helping transport fatty acid-fuel through cell membranes and into the mitochondria. The more ALC, the more fuel, the more vigorous the combustion or metabolism, the more energy produced, and the more efficiently and brightly the mitochondria perform. ALC also protects the brain cells' mitochondria from age-related decay due to attacks from free radical chemicals. (Ann N Y Acad Sci. 2004 Jun;1019:406-11.)

So if ALC is lost to aging, why not replenish it and see what happens? Research studies done by Drs. Ames and Hagen have shown that there is strong evidence that ALC produces a strong rebound of energy. Their studies have shown that free radical damage to mitochondria may be substantially curbed by taking a combination of acetyl-L-carnitine and alpha lipoic acid. As well, there has been new research showing that acetyl-L-carnitine may delay the progression of age-related cognitive decline and Alzheimer's disease. (Ann N Y Acad Sci. 2004 Nov;1033:108-16. Ann N Y Acad Sci. 2004 Jun;1019:406-11.)

According to a recent study, the progression of mild cognitive impairment, which is thought to precede Alzheimer's, was slowed within three months of taking high doses of ALC, between 1,500 to 3,000 mg daily. (Int Clin Psychopharmacol. 2003 Mar;18(2):61-71.)

How safe is it?

Acetyl-L-carnitine is considered overall to be safe, but some experts suggest that individuals may react differently, and could become over stimulated. Dr. Ames recommends a dose of 500 mg twice daily.

Talk with your doctor, pharmacist, or nurse about how much acetyl-L-carnitine you should take. The amount depends on the strength of the medicine and the reason you are taking it. Do not take more acetyl-L-carnitine or take it more often than what is written on the directions.

Note: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

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